Disease Progression Graph

Meningococcal disease is rare, easily misdiagnosed, unpredictable, and potentially deadly ¹
Disease progression is often rapid and may progress from flu-like symptoms to death within 24 hours ^2,3

Slide across to see an example of the progression of symptoms of meningococcal disease over a 24 hour period.

Hours

Not a real patient. Images are a recreation of a real case of meningococcal disease.
Adapted from Thompson et al, 2006 ²

References:
1. Rosenstein NE, Perkins BA, Stephens DS, et al. Meningococcal disease. N Engl J Med. 2001;344(18):1378–1388.
2. Thompson MJ, Ninis N,Perera R, et al. Clinical recognition of meningococcal disease in children and adolescents. Lancet. 2006;367(9508):397–403.
3. Van Deuren M el al. Update on Meningococcal Disease with Emphasis on Pathogenesis and Clinical Management. Clin Microbiol Rev 2000;13(1): 144-166.