Seretide is indicated in the regular treatment of asthma where use of a combination product (long-acting β2 agonist and inhaled corticosteroid) is appropriate:
Or
The recommended dose of Seretide Evohaler 50/25, 125/25 or 250/25 is two inhalations, twice daily.
Seretide Evohaler comes in three different doses, allowing flexibility of dosing for your patient with asthma at low, medium and high dose inhaled steroid4
Seretide Evohaler 50/25 is licensed for use in paediatric asthma for patients 4 years and above.4
Low Dose (50/25 two puffs B.D)
£17.46
Medium Dose (125/25 two puffs B.D)
£23.45
over £5 cheaper than Fostair 100/6 (two puffs B.D)1,2
High Dose (250/25 two puffs B.D)
£29.32
same price as Fostair 200/6 (two puffs B.D)2,5
Seretide is proven to achieve and maintain guideline-defined asthma control3
An estimated
patients* achieved asthma control and remained controlled after 1 year
*GOAL Study Stratum 2 patients defined as those patients who were on 500 μg or less of beclomethasone propionate daily or equivalent.
Patients should not need their rescue inhaler
6 days a week6
rescue free days with Seretide*6
*GOAL Study Stratum 2 patients defined as those patients who were on 500 μg or less of beclomethasone propionate daily or equivalent. The GOAL data has been extrapolated from over one year into one week.
Reduced risk of exacerbations with Seretide7,8
in the risk of severe exacerbations in patients with at least one exacerbation vs fluticasone propionate (p<0.01)7
*The absolute risk reduction compared with ICS alone is 2% (incidence of 8% with Seretide compared to 10% with ICS alone)
in the risk of 2 or more exacerbations over 1 year vs fluticasone propionate (p<0.01)8
†Absolute risk reduction is 13% (4.2% risk of ≥2 exacerbations with Seretide vs 17.4% with ICS alone).
Seretide Evohaler is over £5 cheaper than Fostair at medium dose1,2, and is the same price as Fostair at high dose2,5
| Dose | Seretide Evohaler | Fostair |
|---|---|---|
| Low | 50/25 (2 puffs B.D) | 100/6 (1 puff B.D) |
| Medium | 125/25 (2 puffs B.D) | 100/6 (2 puffs B.D) |
| High | 250/25 (2 puffs B.D) | 200/6 (2 puffs B.D) |
Seretide Evohaler 50/25 is licensed for Children 4 years and older. Fostair is not licensed for use in under 18's.
Seretide Evohaler 50/25 has a license for paediatric asthma for patients 4 years and above, and all
strengths are licensed in adolescent asthma4.
Fostair is not recommended for children & adolescents under 18 years9
The optimal particle size range for delivery to the lungs is 1-5um. Seretide particles are within this range10
There is no evidence that extrafine particles are associated with additional clinically relevant benefits compared with Seretide11,12
This was observed for a number of efficacy endpoints in an extensive scientific literature review and systematic analysis of RCT data, including:
Therefore you can be confident that particle size does not need to be a factor when choosing between Seretide and Fostair.
When clinically indicated, maintenance and reliever therapy (MART) can be a viable option for patients. However, are you aware of some of its limitations?
Less than 20% of MART-treated patients achieved control, according to GINA criteria13,14
MART-treated patients are only rescue free 4 days a week and many still use a separate reliever15
1 in 5 MART-treated patients have a severe exacerbation each year15
Provides a numerical score that helps healthcare professionals and their patients determine if asthma symptoms are well controlled.
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This Placebo Demonstration Device helps healthcare professionals show patients how to use the Evohaler device correctly.
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How to Use Patient Leaflet Pad to support patients to correctly use their Evohaler on its own and with a Volumatic Spacer.
Order nowAdverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/ or search for MHRA Yellowcard in the Google Play or Apple App store. Adverse events should also be reported to GlaxoSmithKline on 0800 221 441.
Seretide is a registered trademark of the GlaxoSmithKline group of companies
PM-GB-FPS-WCNT-200001 (2.0) October 2020
Seretide (salmeterol/fluticasone propionate) Evohaler SmPC
What is Seretide
