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SHINGRIX dosing and administration

Recommended dosing*

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Non-live SHINGRIX is for intramuscular injection, given as a 2-dose series. 1

2-dose series:

The second dose of SHINGRIX can be administered any time between 2–6 months after the first dose.

2-dose series:

The second dose of SHINGRIX can be administered any time between 2-6 months after the first dose

2-dose series:

The second dose of SHINGRIX can be administered any time between 2-6 months after the first dose

2-dose series:

The second dose of SHINGRIX can be administered any time between 2-6 months after the first dose

Supplied as 2 vials for reconstitution:

SHINGRIX is to be reconstituted only with the accompanying adjuvant suspension.

Refrigerate, do NOT freeze:

Prior to reconstitution, the vaccine should be stored between 2°C and 8°C. After reconstitution, the vaccine should be used promptly. If not possible, the vaccine is stable for 6 hours after reconstitution when refrigerated, after which it should be discarded.

Intramuscular (IM) injection only:

Preferably in the deltoid muscle. 

 

Make sure your patients get both doses of SHINGRIX 1

Steps to consider to ensure your patients complete the 2-dose series 1

Explain the importance of 2 doses to your patient 1

Schedule the follow-up immediately:

Patients can receive the second dose any time between 2–6 months after the first dose. 1

Reminders:

  • Once you set a date, have your patients place a reminder in their calendar.
  • Encourage your patients to visit SHINGRIX.ca to sign up to receive text or email reminders.

How to reconstitute SHINGRIX 1

SHINGRIX is to be reconstituted only with the accompanying adjuvant suspension:

1. Withdraw the entire content of the vial containing the suspension into a sterile syringe.

2. Add the entire contents of the syringe into the vial containing the lyophilized powder.

3. Shake gently until the lyophilized powder is completely dissolved. It should be an opalescent, colourless to pale brownish liquid.

4. Inspect the vaccine for any foreign particulate matter and/or variation of appearance. If either is observed, do not administer the vaccine.

5. Withdraw the entire contents of the vial containing the reconstituted vaccine into a sterile syringe.

6. Change the needle so that you are using a new needle to administer the vaccine.

* Refer to the product monograph for complete dosing and administration information.

 

Reference:

  1. SHINGRIX Product Monograph. GlaxoSmithKline Inc., October 13, 2017.