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Dosage & administration

Method of administration 1-4

Augmentin is for oral use.

Augmentin should be administered at the beginning of a meal to minimise potential gastrointestinal intolerance and optimize the absorption of amoxicillin / clavulanic acid.

Posology

Adults and children >= 40 kg

Augmentin 1gr Tablets (875 mg amoxicillin and 125 mg of clavulanic acid): 1

  • standard dose (for all indications): 875 mg/125 mg two times a day;

  • higher dose (particularly for infections such as otitis media, sinusitis, lower respiratory tract infections and urinary tract infections): 875 mg/125 mg three times a day

Augmentin 625mg Tablets (500 mg amoxicillin and 125 mg of clavulanic acid): 2

One 500 mg/125 mg dose taken three times a day.

Children < 40 kg

Augmentiun 457 Suspension (80 mg amoxicillin and 11,4 mg of clavulanic acid per 1 ml suspension): 3

  • 25 mg/3.6 mg/kg/day to 45 mg/6.4 mg/kg/day given as two divided doses.

  • up to 70 mg/10 mg/kg/day given as two divided doses may be considered for some infections (such as otitis media, sinusitis and lower respiratory tract infections).

Adults and children >40 kg should be treated with the adult formulations of Augmentin.

Augmentin ES (120 mg amoxicillin and 8.58 mg of clavulanic acid per 1 ml suspension): 4

Children < 40 kg (aged > 3 months)

Body Weight Kg  Dosage ml
3 1,1 ml - BD
4 1,5 ml - BD
5 1,9 ml - BD
6 2,3 ml - BD
7 2,6 ml - BD
8 3,0 ml - BD
9 3,4 ml - BD
10 3,8 ml - BD
11 4,1 ml - BD
12 4,5 ml - BD
13 4,9 ml - BD
14 5,3 ml - BD
15 5,6 ml - BD
16 6,0 ml - BD
17 6,4 ml - BD
18 6,8 ml - BD
19 7,1 ml - BD
20 7,5 ml - BD
21 7,9 ml - BD
22 8,3 ml - BD
23 8,6 ml - BD
24 9,0 ml - BD
25 9,4 ml - BD
26 9,8 ml - BD
27 10,1 ml - BD
28 10,5 ml - BD
29 10,9 ml - BD
30 11,3 ml - BD
31 11,6 ml - BD
32 12,0 ml - BD
33 12,4 ml - BD
34 12,8 ml - BD
35 13,1 ml - BD
36 13,5 ml - BD
37 13,9 ml - BD
38 14,3 ml - BD
39 14,6 ml - BD
40 15,0 ml - BD

The recommended dose of Augmentin suspension is 90/6.4 mg/kg/day in two divided doses. 

Treatment should not be extended beyond 14 days without review

There are no clinical data on Augmentin ES in children under 3 months of age.

There is no experience with Augmentin ES suspension in adults and children >= 40 kg, and therefore no dose recommendation can be given.


The above information does not contain all information on Posology and method of administration. For further information on Posology and method of administration please consult the Full SmPC which you can request from GSK or you can access from the Website of the Pharmaceutical Services of the Ministry of Health

References:

  1. SmPC Augmentin Tablets 1gr 
  2. SmPC Augmentin Tablets 500/125 mg 
  3. SmPC Augmentin suspension 457 mg/5 ml.
  4. SmPC Augmentin ES 600 mg/42.9 mg/5 ml

Before prescribing please consult the full SPC which you can request from GSK or access on the website of the Pharmaceutical Services of the Ministry of Health 
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