Ellipta (umeclidinium/vilanterol) SmPCDON'T HOLD BACKStart with Anoro
as Initial Maintenance Therapy
in symptomatic COPD patients
What is Anoro Ellipta?
Indication
Anoro Ellipta is indicated as a maintenance bronchodilator treatment to relieve symptoms in adult patients with COPD1.
Dosing
The recommended and maximum dose of Anoro Ellipta (UMEC/VI 55/22 mcg) is one inhalation once a day. If a dose is missed the next dose should be taken at the usual time the next day1.
MeetHannah*
*Fictional patient
mMRC, modified Medical Research Council
CAT, COPD assessment test
FEV1, forced expiratory volume in one second
SABA, short-acting beta2 agonist
mMRC, modified Medical Research Council
CAT, COPD assessment test
FEV1, forced expiratory volume in one second
SABA, short-acting beta2 agonist
In a post hoc, pooled analysis of 3 RCTs at 24 weeks in patients not on maintenance therapy (for ≥ 30 days before screening), Anoro demonstrated:
(p<0.001)
with an extra 146mL improvement in trough FEV14,5
Initial maintenance therapy:
LAMA or LAMA/LABA?
A cross-sectional analysis of 818 COPD patients found that, despite treatment with tiotropium monotherapy, approximately 50% continue to suffer moderate to severe breathlessness (mMRC≥2)3.
Start with Anoro as an initial maintenance therapy in your symptomatic adult COPD patients.
Anoro was well tolerated and demonstrated a safety profile comparable to tiotropium HandiHaler4.
Think all
LAMA/LABAs
are the same?
In a 8 week, open-label, crossover study in patients not on maintenance therapy (for ≥ 2 weeks prior to randomisation)6:
Anoro provided a 38% reduction in rescue medication usage vs Spiolto (difference: 0.25 puffs/day)6.Anoro was well tolerated and demonstrated a safety profile comparable to Spiolto Respimat6.
Anoro demonstrated:
(p<0.001)
with an extra 52 mL improvement in trough FEV16
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Formulary
Information to support commissioners and healthcare professionals when making an Anoro formulary application
View evidence summary
Get started with Anoro Ellipta
for patients with COPD like Hannah
Identify patients like Hannah using the CAT score pad
COPD assessment test (CAT) pad questionnaire to measure the impact of COPD on a person’s life.
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Can your patient use the Ellipta device effectively?
Ellipta inhalation training whistle that helps patients understand the correct inspiratory flow needed to use the Ellipta device.
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Help demonstrate the Ellipta device to patients like Hannah
Ellipta Demonstration device for healthcare professionals to show patients how to use the Ellipta device correctly.
Order nowReferences
- 1. Anoro SmPC
- 2. Stenton et al. Occupational Medicine; 2008: 58:226–227
- 3. GSK data on file UK/UCV/0114/14
- 4. Maleki-Yazdi M et al. Adv Ther 2016; 33:2188-2199.
- 5. GSK DATA on file: RF/UCV/0112/15.
- 6. Feldman G.J et al. Adv Ther 2017; 34:2518–2533
- 7. Riley J et al. Int J Chron Obstruct Pulmon Dis 2016; 11:1873-1880.
- 8. Svedsater H et al. BMC pulm Med 2013; 13:72-86.
- 9. Van der Palen J et al. NPJ Primare Respir Med 2016; 26:16079.
Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/ or search for MHRA Yellowcard in the Google Play or Apple App store. Adverse events should also be reported to GlaxoSmithKline on 0800 221 441.
© 2020 GSK Group of Companies or its licensor. Trademarks are the property of their respective owners.
Anoro Ellipta was developed in collaboration with Innoviva.
Last updated: November 2020. PM-GB-UCV-WCNT-190010 V3.0