Seretide vs. other ICS/LABAs
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With proactive regular dosing, Seretide achieves and maintains well controlled asthma2
With Seretide, 3 out of 4 patients who achieved at least well controlled asthma, remianed controlled after 1 year2
With Seretide, asthma patients shouldn’t need their rescue inhaler 6 days out of 7*3.
*Patients who were stratum 2 of the GOAL study i.e on low dose ICS, the GOAL data has been extrapolated from over one year into one week
Seretide significantly reduces the risk of severe exacerbations by 21%* compared to an ICS alone in patients with a history of exacerbations (p<0.001)4
*The absolute risk reduction compared with an ICS alone is 2%. Incidence of 8% (n=480/5834) with Seretide compared to 10% (n=597/5845) with an ICS alone.
(≥1/100 to <1/10)
|Candidiasis of the mouth and throat, pneumonia*, bronchitis*, hypokalaemia*, throat irritation, hoarseness/dysphonia, sinusitis*, contusions*, muscle cramps, traumatic fractures*, arthralgia, myalgia|
(≥1/1000 to <1/100)
|Cutaneous hypersensitivity reactions, respiratory symptoms (dyspnoea), hyperglycaemia, anxiety, sleep disorders, tremor, cataract, palpitations, tachycardia, atrial fibrillation, angina pectoris|
(≥1/10,000 to <1/1000)
|Oesophageal candidiasis, angioedema (mainly facial and oropharyngeal oedema), respiratory symptoms (bronchospasm), anaphylactic reactions including anaphylactic shock, Cushing’s syndrome, Cushingoid features, adrenal suppression, growth retardation in children and adolescents, decreased bone mineral density, behavioural changes including psychomotor hyperactivity and irritability (predominantly in children), glaucoma, cardiac arrhythmias (including supraventricular tachycardia and extrasystoles), paradoxical bronchospasm
(frequency cannot be estimated)
|Depression, aggression (predominantly in children), blurred vision|