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Ready to vaccinate with SHINGRIX▼ (herpes zoster vaccine, recombinant, adjuvanted)?

Get the information you need to administer SHINGRIX to adults 50 years of age and older with confidence.1,2

SHINGRIX reconstitution instructions

Follow these instructions when reconstituting and administering SHINGRIX.1,2

SHINGRIX vaccine MUST be reconstituted prior to administration.1,2

Prescribing information (GB)

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Prescribing information (NI)

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Dosing and administration

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SHINGRIX is given as a 2-dose schedule

For adults 50 years of age and older, the second dose should be administered 2 months after the first dose. If flexibility is necessary, the second dose can be administered between 2-6 months after the first dose.1,2

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SHINGRIX co-administration

SHINGRIX can be co-administered with several different vaccines. For more information on co-administration of SHINGRIX and other vaccines, please consult the SHINGRIX Summary of Product Characteristics.1,2

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SHINGRIX should be refrigerated. DO NOT FREEZE

Store in a refrigerator 2°C - 8°C.1,2

After reconstitution, the vaccine should be used immediately; if this is not possible, the vaccine should be stored in a refrigerator (2°C - 8°C). If not used within 6 hours, it should be discarded.1,2

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SHINGRIX is supplied as 2 vials for reconstitution and is for intramuscular injection only, preferably in the deltoid muscle1,2

The vial containing the powder (antigen) and the vial containing the suspension (adjuvant) MUST be reconstituted prior to administration.1,2

For further safety information on SHINGRIX including a full list of adverse reactions reported during post-marketing surveillance, please consult the Summary of Product Characteristics.1,2

Making it part of your routine

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Explain their risk of shingles:

1. Age-related decline in immunity puts patients 50 years of age and older at an increased risk of developing shingles.3,4

2. Shingles is a painful disease that can have serious and long-lasting complications.5

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Explain the benefit of protection from both doses:

1. Dosing and administration: It takes 2 doses to help protect adults 50 years of age and older with SHINGRIX.1,2

2. SHINGRIX is given as a two-dose schedule, an initial dose followed by a second dose 2 months later. If flexibility is necessary, the second dose can be administered between 2-6 months after the first dose.1,2

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Tell them what to expect:

1. The specific side effects they are likely to encounter.

2. How long any side effects may last.

For further safety information on SHINGRIX including a full list of adverse reactions reported during post-marketing surveillance, please consult the Summary of Product Characteristics.1,2

SHINGRIX vaccine MUST be reconstituted prior to administration.1,2

Ensuring two-dose schedule completion

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Schedule the follow-up promptly and encourage reminders:

SHINGRIX is given as a 2-dose schedule, an initial dose followed by a second dose 2 months later.1,2

Once a date is set for their second dose, advise your patients to place a reminder in their personal calendar.
Additionally, use a telephone call to remind patients of their upcoming appointment.

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GSK resources

Support your patients and practice with healthcare resources on our resources page (delivery is free on all orders).

For further safety information on SHINGRIX including a full list of adverse reactions reported during post-marketing surveillance, please consult the Summary of Product Characteristics.1,2

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  • SHINGRIX list price: £160
  • SHINGRIX can be purchased from AAH Pharmaceuticals or Alliance Healthcare (Distribution) Ltd.

For more information on SHINGRIX, contact a GSK representative.

Learn more about SHINGRIX

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How efficacious is SHINGRIX?

SHINGRIX demonstrated >90% efficacy against shingles in adults 50 years of age and older based on pooled data from two large, phase 3 randomised controlled trials.1,2,6,7

VIEW EFFICACY DATA

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Who can benefit from SHINGRIX?

There is a 1 in 4 lifetime risk of developing shingles.8 Age-related decline in immunity puts patients 50 years of age and older at an increased risk of developing shingles.3,4

View Patient Profiles

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Learn more about the safety profile of SHINGRIX.

The majority of local and systemic adverse reactions were mild to moderate and transient, based on two large, phase 3 randomised controlled trials. Reactions reported as severe lasted 1 to 2 days.1,2,6,7

Explore Safety Data

References

  1. Shingrix, GB Summary of Product Characteristics (SPC)
  2. Shingrix, NI Summary of Product Characteristics (SPC)
  3. Gauthier et al. Epidemiology and costs of herpes zoster and postherpetic neuralgia in the United Kingdom. Epidemiol infecti. 2009 137 38-472.
  4. Kimberlin DW, Whitley RJ. Varicella-zoster vaccine for the prevention of herpes zoster. N Engl J Med. 2007 Mar;356 (13):1338-43.
  5. UK NICE Clinical Knowledge Summaries. What are the complications? October 2020. Accessed July 2021.
  6. Lal H, Cunningham AL, Godeaux O, Chlibek R, Diez-Domingo J, Hwang S-J, et al. Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. N Engl J Med. 2015 May;372 (22):2087-96.
  7. Cunningham AL, Lal H, Kovac M, Chlibek R, Hwang S-J, Diez-Domingo J, et al. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. N Engl J Med. 2016 Sep;375 (11):1019-32.
  8. DH Green Book ch 28a - Shingles. February 2016. Accessed July 2021.
  9. Public Health England Green Book. Immunisation Procedures Chapter 4. Jun 2012.

Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/ or search for MHRA Yellowcard in the Google Play or Apple App store. Adverse events should also be reported to GlaxoSmithKline on 0800 221 441

SHINGRIX is owned by or licensed to the GSK group of companies.
© 2022 GSK group of companies or its licensor.
Trade marks are owned by or licensed to the GSK group of companies.

February 2022 | PM-GB-SGX-WCNT-210011 (V2.0)