Pregnancy prevention programme
Toctino (alitretinoin), is licensed in the United Kingdom as an oral treatment for patients suffering from severe chronic hand eczema that does not respond to potent topical corticosteroid therapy. Toctino should only be prescribed by dermatologists or physicians with experience in the use of systemic retinoids.
Toctino (alitretinoin) is a naturally occurring, physiologic derivative of vitamin A and belongs to the well studied family of retinoids, which are all teratogens; therefore, Toctino (alitretinoin) is strictly contraindicated in pregnancy, and in women of child-bearing potential unless strict pregnancy testing and contraception is followed before, during and one month after cessation of treatment.
A summary of the requirements: Dear HCP letter
Guidance for healthcare professionals
Checklist for prescribing
to female patients
for female patients