Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol)

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Trelegy Ellipta pack shot
A simple choice. One inhaler, easy to use and quick to teach1

With >99% of patients able to generate the inspiratory flow required, Ellipta ensures even your severe COPD patients get the dose they need2,3

Dosing | The recommended and maximum dose is one inhalation of Trelegy Ellipta 92/55/22 micrograms once daily, at the same time each day. If a dose is missed the next dose should be inhaled at the usual time the next day.4

Don’t settle for a MDI, when you can give them the preferred, easy-to-use Ellipta device1

See below to compare critical errors of commonly used devices

Critical errors graph

Adapted from Van der Palen J et al. 2016

Open label, placebo inhaler, crossover comparison in patients naïve to Ellipta and the comparator inhaler (p<0.001 for all comparisons)

This study assessed critical errors in the most common type of MDI where shaking prior to use is required. The most common critical error with an MDI was poor actuation and inhalation coordination. *Defined as errors that are likely to result in no, or minimal medication being delivered to the lungs
In another phase IV, randomised, open label, multicentre effectiveness study the percentage of patient at week 24 with >1 critical error in inhaler technique was 6% in the Trelegy treatment group and 3% in the non-Ellipta MITT group. Odds ratio: 1:99; p=0.103(NS)10

83% of COPD Triple Therapy patients on multiple inhalers in the UK are managing once and twice daily dosing concurrently6

Where patients are using several classes of inhalers and poor inhaler technique is identified with once device, the DPI class should be prioritised if the patient is able to use these safely.7

Different triple therapy combinations

This figure does not represent all inhalers of all possible combinations. Trademarks are the property of their perspective owners.

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Trelegy Ellipta pack shot

A single inhaler triple therapy

How to Use the Trelegy Ellipta Inhaler

See how easy it is for patients to use the Ellipta inhaler device as part of daily life.

ORDER DEMO DEVICE

Support your patients starting on Trelegy Ellipta

Ellipta demo device

Demonstration device

Demonstration device for healthcare professionals to show patients how to use the Ellipta device correctly. Visit resources page to order.

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Nurse with patient

Provide patient resources

Support your patients with Ellipta information leaflet, Trelegy support booklet, and Medicine change guides for patients moving on to Trelegy

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Ellipta Inhaler training device

Ellipta inhalation trainer

For patients who have been prescribed an Ellipta inhaler, check that they are performing the correct inhaler technique by ordering a training whistle.

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Prescribing Information Links

Trelegy Ellipta Prescribing Information (pdf)

Seretide Accuhaler Prescribing Information (pdf)

Incruse Ellipta Prescribing information (pdf)

Relvar Ellipta Prescribing Information (pdf)

Trelegy Ellipta OD is indicated for maintenance treatment in adult patients with moderate to severe chronic obstructive pulmonary disease (COPD) who are not adequately treated by a combination of an inhaled corticosteroid and a long-acting β2-agonist or a combination of a long-acting β2-agonist and a long-acting muscarinic antagonist.4

Seretide accuhaler is indicated for symptomatic treatment of patients with COPD with a FEV1 <60% predicted normal (prebronchodilator) and a history of repeated exacerbations, who have significant symptoms despite regular bronchodilator therapy5

Relvar Ellipta OD is indicated for the symptomatic treatment of adults with COPD with a FEV1<70% predicted normal (post-bronchodilator) and an exacerbation history despite regular bronchodilator therapy.8

Incruse Ellipta OD is indicated for maintenance bronchodilator treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD)9

Footnotes

ICS, inhaled corticosteroid; LABA, long-acting β2-agonist; LAMA, long-acting muscarinic antagonist; DPI, dry powder inhaler; MDI, metered-dose inhaler; pMDI, pressurised metered-dose inhaler, OD, once daily.

References

  1. van der Palen J et al. NPJ Prim Care Med 2016; 26:16079
  2. Anderson M, et al. Int J Chron Obstruct Pulmon Dis. 2021 Apr12;16:933-943
  3. Prime D, et al. CHEST. 2019;156:A1786
  4. Trelegy SmPC
  5. Seretide SmPC
  6. Analysis by GSK based on IQVIA DRx, COPD Triple Therapy data set, patients, February 2021. REF-124866
  7. BTS Position Statement - The environment and lung health 2020
  8. Relvar Ellipta SmPC
  9. Incruse Ellipta SmPC
  10. Halpin, D et al 2021. INTREPID: single- versus multiple inhaler triple therapy for COPD in usual clinical practice. ERJ Open Research, pp00950-2020. No 824

 

Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/ or search for MHRA Yellowcard in the Google Play or Apple App store. Adverse events should also be reported to GlaxoSmithKline on 0800 221 441.

August 2022 | PM-GB-FVU-WCNT-200008 (V4.0)