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For which of my patients with COPD is TRELEGY Ellipta most appropriate?


What we know about patients like Alexander

In a database study of over 63,000 patients on COPD maintenance treatment:*

  • 43% of patients had exacerbations in the last 12 months**1 2

In the same study, of over 43,000 patients with data available:

  • 52% of patients still experienced ongoing breathlessness1 2


The impact of exacerbations on your patients

Ultimately, every patient may recognise and experience a COPD exacerbation differently. Some may end up in hospital, some may be housebound, whilst others may be able to better manage at home. Some patients understand the symptoms of an exacerbation more than others, some patients only know how it makes them feel.3


You know when you’re underwater and you’re trying to get out and you get that desperate feeling – that’s how an attack feels.

Could TRELEGY Ellipta help reduce your patients’ COPD exacerbations?

Explore efficacy data


The patient need for a simple treatment routine

Complicated treatment routines may lead to missed doses, reduced adherence and worse treatment outcomes.9-11 Complicated routines could be caused by the need for patients to use different inhalers, or to take multiple daily doses from the same inhaler.11 12

  • Multiple daily dosing may results in reduced adherence to their treatment routine10

How could TRELEGY’s dosing and the Ellipta inhaler make a difference to your patients?

Discover more

Footnotes
*Patients aged ≥40, receiving one of the following: LAMA, LABA, LAMA/LABA or ICS/LABA.1
**Defined as ≥2 exacerbations without hospitalisation, ≥1 hospitalisation for COPD, or both.
1
A real world clinical practice study of 55,076 patients with COPD in the United States between 1998 and 2006. Patient adherence was measured using proportion of days covered (PDC), which was defined as the proportion of days in a given time interval that a patient had a drug available measured over a one-year interval.10

Abbreviations
COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in one second; ICS, inhaled corticosteroid; LABA, long-acting β2-agonist; LAMA, long-acting muscarinic antagonist; OD, once-daily

References:

  1. Rebordosa C et al. Pharmacoepidemiol Drug Saf 2018 May 8. doi: 10.1002/pds.4448. [Epub ahead of print].
  2. Rebordosa C et al. Pharmacoepidemiol Drug Saf 2018 May 8. doi: 10.1002/pds.4448. [Epub ahead of print]: Online supporting information.
  3. Williams V et al. NPJ Prim Care Respir Med 2014; 24:14062.
  4. Barnes PJ et al. Nat Rev Dis Primers 2015; 1:15076. doi: 10.1038/nrdp.2015.76.
  5. Donaldson G et al. Thorax 2002; 57(10): 847–852.
  6. Seemungal TA et al. Am J Respir Crit Care Med 1998; 157(5):1418–1422.
  7. Halpin DMG et al. Respir Med 2017; 128:85–91.
  8. Donaire-Gonzalez D et al. Eur Respir J. 2015; 46(5):1281–1289.
  9. Bourbeau J et al. Thorax 2008; 63:831–838.
  10. Toy EL et al. Respir Med 2011; 105(3):435–441.
  11. Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease (GOLD) 2019. Available at https://goldcopd.org/gold-reports/ [Accessed December 2018]
  12. Melani AS et al. Respir Med 2011; 105:930–938.
  13. TRELEGY Ellipta SmPC, 2018 Available at www.medicines.ie [Accessed December 2018].

TRELEGY Ellipta was developed in collaboration with INNOVIVA Inc.

Adverse events should be reported to the Health Products Regulatory Authority (HPRA) using an Adverse Reaction Report Form obtained either from the HPRA or electronically via the website at www.hpra.ie. Adverse reactions can also be reported to the HPRA by calling: (01) 6764971. Adverse events should also be reported to GlaxoSmithKline on 1800 244 255.

▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions.

© 2018 GSK Group of Companies or its licensor. Trademarks are the property of their respective owners

TRELEGY Ellipta OD is indicated for maintenance treatment in adult patients with moderate-to-severe COPD who are not adequately treated by a combination of an ICS and a LABA, or a combination of a LAMA and a LABA13