The GSK DTaP vaccine portfolio provides consistent DTaP antigen content from
6 weeks through 6 years of age (prior to the seventh birthday)1-3
DU=D-antigen units; HBsAg=hepatitis B surface antigen; Lf=limits of flocculation.
Because the pertussis antigens contained in INFANRIX and KINRIX are the same as those in PEDIARIX, children who have received a 3-dose series with PEDIARIX should receive INFANRIX as their fourth dose of DTaP and either INFANRIX or KINRIX as their fifth dose of DTaP, according to the respective Prescribing Information for these vaccines.1
DTaP=diphtheria, tetanus, and acellular pertussis; IPV=inactivated poliovirus vaccine.
- PEDIARIX as a primary series: Three doses of 0.5 mL each, by intramuscular injection, at 2, 4, and 6 months of age (at intervals of 6 to 8 weeks, preferably 8 weeks). The first dose may be given as early as 6 weeks of age. Three doses of PEDIARIX constitute a primary immunization course for diphtheria, tetanus, pertussis, and poliomyelitis and the complete vaccination course for hepatitis B. 1
According to the Centers for Disease Control and Prevention (CDC), administration of a total of 4 doses of HepB vaccine is permitted when a combination vaccine containing HepB is administered after the birth dose. 4
A 3-dose series of PEDIARIX may be administered to infants born of HBsAg-negative mothers and who received a dose of hepatitis B vaccine at or shortly after birth. However, data are limited regarding the safety of PEDIARIX in such infants 1
- Booster immunization following PEDIARIX: Because the pertussis antigens contained in INFANRIX and KINRIX are the same as those in PEDIARIX, these children should receive INFANRIX as their fourth dose of DTaP and either INFANRIX or KINRIX as their fifth dose of DTaP, according to the respective Prescribing Information for these vaccines. KINRIX or another manufacturer's IPV may be used to complete the 4-dose IPV series according to the respective Prescribing Information 1
Sufficient data on the safety and effectiveness of interchanging PEDIARIX, INFANRIX, and KINRIX with DTaP-containing vaccines from different manufacturers are not available. 1-2
The GSK Portfolio of DTaP-containing Vaccines: Benefits That May Help Streamline the Vaccination Process by Reducing the Number of Steps
- PEDIARIX, INFANRIX, and KINRIX are available in Tip-Lok® syringes
- Single unit-dose prefilled for your conveniencea
- Luer-Lok® adapter fits virtually any needle
- The tip caps of the prefilled syringes contain natural rubber latex, which may cause allergic reactions
- INFANRIX and KINRIX are also available in 0.5-mL single-dose vials. The vial stopper does not contain latex
a Each syringe delivers the labeled dose.
- Prescribing Information for PEDIARIX.
- Prescribing Information for INFANRIX.
- Prescribing Information for KINRIX.
- Centers for Disease Control and Prevention. Recommended Immunization Schedules for Persons Aged 0 Through 18 Years--United States, 2016. http://www.cdc.gov/vaccines/schedules/
downloads/child/0-18yrs-child-combined-schedule.pdf. Accessed November 12, 2019.
- American Medical Association. CPT (Current Procedural Terminology) 2016 Professional Edition. Chicago, IL: American Medical Association; 2015.