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Get to know the CDC recommendation for MenACWY vaccination

CDC recommends 2 doses of MenACWY—a primary dose at age 11-12 and a booster at 16—for all adolescents1

The CDC emphasizes the importance of vaccines for 16-year-olds.

In 2017, the CDC updated their immunization schedule for adolescents ≤18 years of age, adding a 16-year-old age column to their table of recommendations.2,3

The change was designed to address a problem.

According to the Immunization Action Coalition, the new “16-year-old” column brings much-needed attention to the fact that several CDC-recommended vaccinations due to be administered at 16 years of age are being overlooked by many providers.2

There are 2 different types of vaccines to help protect against the 5 vaccine-preventable meningococcal serogroups: 1 for serogroups ACWY and 1 for serogroup B.4,5

 

According to 2018 CDC data, only 51% of 17-year-olds received a primary AND booster dose of MenACWY vaccine6

CDC=Centers for Disease Control and Prevention; MenACWY=meningococcal serogroups A, C, W, Y.

References

  1. Centers for Disease Control and Prevention. Prevention and control of meningococcal disease: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. 2013;62(2):1-30.
  2. Wexler D. Immunization Action Coalition. Technically speaking: New “16-year-old vaccination platform” highlighted in 2017 US child/teen immunization schedule. http://www.immunize.org/technically-speaking/20170222.asp. Updated May 26, 2017. Accessed February 5, 2020.
  3. Centers for Disease Control and Prevention. Immunization schedules: Recommended child and adolescent immunization schedule for ages 18 years or younger, United States, 2020. https://www.cdc.gov/vaccines/schedules/hcp/imz/child-adolescent.html. Reviewed February 3, 2020. Accessed February 5, 2020.
  4. Centers for Disease Control and Prevention. Meningococcal vaccination for adolescents: Information for healthcare professionals. http://www.cdc.gov/vaccines/vpd/mening/hcp/adolescent-vaccine.html. Updated July 26, 2019. Accessed February 3, 2020.
  5. Centers for Disease Control and Prevention. Vaccines and preventable diseases: Meningococcal vaccination. https://www.cdc.gov/vaccines/vpd/mening/index.html. Updated July 26, 2019. Accessed February 11, 2020.
  6. Centers for Disease Control and Prevention. National, regional, state, and selected local area vaccination coverage among adolescents aged 13–17 years—United States, 2018. MMWR. 2019;68(33):718-723.

INDICATION

MENVEO is a vaccine indicated for active immunization to prevent invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, Y, and W-135. MENVEO is approved for use in persons aged 2 months through 55 years. MENVEO does not prevent N. meningitidis serogroup B infections.

IMPORTANT SAFETY INFORMATION FOR MENVEO

  • Severe allergic reaction (eg, anaphylaxis) after a previous dose of MENVEO, any component of this vaccine, or any other CRM197, diphtheria toxoid, or meningococcal-containing vaccine is a contraindication to administration of MENVEO
  • Appropriate medical treatment must be available should an acute allergic reaction, including an anaphylactic reaction, occur following administration of MENVEO
  • Syncope, sometimes resulting in falling injury associated with seizure-like movements, has been reported following vaccination with MENVEO. Vaccinees should be observed for at least 15 minutes after vaccine administration to prevent and manage syncopal reactions
  • Safety and effectiveness of MENVEO have not been evaluated in immunocompromised persons. If MENVEO is administered to immunocompromised persons, including those receiving immunosuppressive therapy, the expected immune response may not be obtained
  • Guillain-Barré syndrome (GBS) has been reported in temporal relationship following administration of another US-licensed meningococcal quadrivalent polysaccharide conjugate vaccine. The decision to administer MENVEO to subjects with a known history of GBS should take into account the potential benefits and risks
  • Apnea following intramuscular vaccination has been observed in some infants born prematurely. The decision about when to administer an intramuscular vaccine, including MENVEO, to an infant born prematurely should be based on consideration of the individual infant’s medical status and the potential benefits and possible risks of vaccination
  • In clinical trials evaluating a primary vaccination dose or series, common solicited adverse reactions with MENVEO among children initiating vaccination at 2 months of age and receiving the four-dose series were tenderness and erythema at injection site, irritability, sleepiness, persistent crying, change in eating habits, vomiting, and diarrhea. Common solicited adverse reactions among children initiating vaccination at 7 months through 23 months of age and receiving the two-dose series were tenderness and erythema at injection site, irritability, sleepiness, persistent crying, change in eating habits, and diarrhea. Common solicited adverse reactions among children aged 2 years through 10 years who received MENVEO were injection-site pain, erythema, irritability, induration, sleepiness, malaise, and headache. Common solicited adverse reactions among adolescents and adults aged 11 through 55 years who received a single dose of MENVEO were pain at the injection site, headache, myalgia, malaise, and nausea. Some events were severe. In a clinical trial evaluating booster dose vaccination among adolescents and adults aged 15 through 55 years, similar rates of solicited adverse reactions were observed following a single booster dose. Common solicited adverse reactions were pain at the injection site and fatigue
  • Vaccination with MENVEO may not result in protection in all vaccine recipients

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