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SLE Patient Case Studies: Brianne

Hypothetical Patient

Brianne is a full-time professional with worsening SLE symptoms that affect her ability to do her day-to-day job.

  • Taking an antimalarial agent alone but is having flares requiring short-term glucocorticoids

Use the SELENA-SLEDAI tool to objectively assess a patient's overall disease activity. It is included in these case studies for the purpose of demonstrating how the variables you may already be evaluating in your clinical practice correlate with the SELENA-SLEDAI disease descriptors

History

  • Diagnosed with SLE 2 years ago
  • For past 6 months, has experienced:
    • Hair loss
    • Increasing pain in her hands and fingers
    • Ulcers on her palate

Medication History

  • Antimalarial for 2 years
  • Moderate dosage of glucocorticoid daily for flares
Lab Values
Hemoglobin (g/dL) 12.2
Platelets (x109/L) 260
WBCs (x109/L) 3.9
Urinalysis Normal
Creatinine (mg/dL) 0.7
Proteinuria (g/day) Normal
Anti-dsDNA (IU/mL) 40
Complement C3 and C4 (mg/dL) 60 and 5
Lymphocytes (x109/L) 1200
WBCs (x10 9/L)
Anti-dsDNA (IU/mL)

SELENA-SLEDAI SCORE: 12 points
(Arthritis 4 points, Mucosal ulcers 2 points, Alopecia 2 points, Elevated anti-dsDNA 2 points, Low complement 2 points)

 

Review Christa’s case study.