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How does Maternal Immunization work?

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Maternal Immunization offers passive immunity to the newborn via transplacental transfer of maternal antibodies. 12

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Data suggests that early third trimester is optimal for immunization with Tdap. 34

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Considerations to evaluate Maternal Immunization.

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In this section:

Maternal immunization offers passive immunity to the newborn via transplacental transfer of maternal antibodies

Optimal timing to vaccinate

Considerations to evaluate Maternal Immunization

 

Tdap: tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine.

References :

  1. Healy CM. Pertussis vaccination in pregnancy. Hum Vaccin Immunother. 2016;12(8):1972-1981.
  2. Gkentzi D, et al. Maternal vaccination against pertussis: a systematic review of the recent literature. Arch Dis Child Fetal Neonatal Ed. 2017;102:F456-F463.
  3. ACOG Committee Opinion. Update on immunization and pregnancy: tetanus, diphtheria, and pertussis vaccination. Number 718, September 2017. [accessed March 2018]; Available at: https://www.acog.org/Resources-And-Publications/Committee-Opinions/Committee-on-Obstetric-Practice/Update-on-Immunization-and-Pregnancy-Tetanus-Diphtheria-and-Pertussis-Vaccination
  4. CDC. Pregnancy and Whooping Cough. For Healthcare Professionals. Vaccinating Pregnant Patients. [accessed March 2018]; Available at: https://www.cdc.gov/pertussis/pregnant/hcp/pregnant-patients.html