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Adherence

A treatment is only effective if a patient takes it. When it comes to Relvar, a significantly greater proportion of patients adhere to their treatment, leading to higher persistence rates with Relvar at 12 months, vs both BUD/Form and BDP/Form.*1

Adherence BUD graph

This graph has been independently created by GSK from the original data. The same results were first published in Parimi M, et al. Adv Ther 2020;37:2916–2931.

Persistent patients graphic

This graph has been independently created by GSK from the original data. The same results were first published in Parimi M, et al. Adv Ther 2020;37:2916–2931.

ADHERENCE VS BDP/F graph

This graph has been independently created by GSK from the original data. The same results were first published in Parimi M, et al. Adv Ther 2020;37:2916–2931.

Persistence VS BDP/F graphic

This graph has been independently created by GSK from the original data. The same results were first published in Parimi M, et al. Adv Ther 2020;37:2916–2931.

Patients initiating FF/VI had a 35% and 31% lower risk of discontinuing treatment compared with BUD/Form and BDP/Form respectively within 1 year after initiation (both p<0.001)1

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Good adherence and quality of life

Good adherence can mean more symptom-free days and improved quality of life, with more stamina for everyday activities.2 See how else Relvar can help your patients.

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Footnotes

*The primary endpoint for this study was persistence measured as time to discontinuation. FF/VI had notably less follow-up time available than comparators due to different launch dates and their consequent availability. Respective unadjusted median time to discontinuation and median follow-up time for each comparison were as follows: 99 and 393 days for FF/VI vs 116.5 and 817 days for BUD/Form; and 97 and 402 days for FF/VI vs 91 and 539 days for BDP/Form. This was a retrospective UK database study in the THIN (The Health Improvement Network) dataset. The primary endpoint was to compare persistence (time to discontinuation) for patients initiating Relvar (n=966), BUD/Form (n=5931) or BDP/Form (n=9607). Adherence was defined as the average percentage of days covered (PDC) over 12 months. ‘Good adherence’ refers to the percentage of patients achieving a PDC ≥80%. The percentage PDC is calculated using the formula: (number of days covered) / (total number days in period) × 100, where “covered” means that the patient had a corresponding filled prescription for that day.1

Abbreviations

AE, adverse event; BDP, beclomethasone dipropionate; BUD, budesonide; CI, confidence interval; FF, fluticasone furoate; Form, formoterol; OR, odds ratio; PDC, percentage of days covered; THIN, The Health Improvement Network; VI, vilanterol.

Relvar Safety Information3

Contraindications
Hypersensitivity to the active substances or to any of the excipients.

Undesirable effects
Very Common: Headache, Nasopharyngitis.

Common: Infections and infestations, Oropharyngeal pain, Sinusitis, Pharyngitis, Rhinitis, Cough, Dysphonia, Abdominal pain, Arthralgia, Back pain, Fractures, Muscle spasms and Pyrexia.

References
  1. Parimi M, et al. Adv Ther 2020;37:2916–2931.
  2. Halterman JS, et al. J Asthma 2011;48:523–530.
  3. Relvar Prescribing Information.

GSK does not recommend, endorse, or accept liability for the 3rd party sites.

For more information, please refer to the prescribing information or contact GlaxoSmithKline via gcc.medinfo@gsk.com
To report Adverse Event/s associated with the use of GSK product/s, please contact us via
gulf.safety@gsk.com
To report quality complaint/s associated with the use of GSK product/s, please contact us via
 Gulf.ProductQualityComplaints@gsk.com

Department of Pharmacovigilance & Drug Information
Drug Safety Center
Ministry of Health, Sultanate of Oman
Phone Nos. 0096822357687 / 0096822357690
Fax: 0096822358489
Email: pharma-vigil@moh.gov.om
Website: https://moh.gov.om/en/

دائرة التيقظ و المعلومات الدوائية
مركز سلامة الدواء
وزارة الصحة, سلطنة عمان
هاتف: 0096822357687 / 0096822357690
0096822358489 :فاكس
pharma-vigil@moh.gov.om :البريد االكتروني
https://moh.gov.om/en/ : الموقع االكتروني

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PM-RCH-FFV-WCNT-250001 Date of preparation: July 2025