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24-hour action

Relvar contains a unique combination of long-lasting molecules – fluticasone furoate and vilanterol.1 This means that once-daily dosing with Relvar provides continuous 24-hour efficacy with no drop in effectiveness towards the end of the 24-hour dosing interval.1–3

24-h action graph

This graph has been reprinted by permission of the publisher Informa UK Limited trading as Taylor & Francis Ltd, http://www.tandfonline.com. The original graph was published in David I Bernstein, Eric D Bateman, Ashley Woodcock, William T Toler, Richard Forth, Loretta Jacques, Carol Nunn, Paul M O'Byrne. Fluticasone furoate (FF)/vilanterol (100/25 mcg or 200/25 mcg) or FF (100 mcg) in persistent asthma. Journal of Asthma 2015;52:1073–1083.

Fluticasone furoate and vilanterol are not licensed as monotherapies for patients with asthma in all markets. Relvar is not indicated for the relief of acute bronchospasm.

Duration of action graph

While therapeutic effect is even seen post-24 hours, the approved and recommended dosing for Relvar is once-daily.1

Reprinted from Respiratory Medicine, Vol 119, Braithwaite I, et al, Randomised, double-blind, placebo-controlled, cross-over single dose study of the bronchodilator duration of action of combination fluticasone furoate/vilanterol inhaler in adult asthma, pp115–121, Copyright © 2016, with permission from Elsevier. The same results were first published in Braithwaite I, et al. Respir Med 2016;119:115–121.

Fluticasone furoate and vilanterol are not licensed as monotherapies for patients with asthma in all markets. Relvar is not indicated for the relief of acute bronchospasm.

Discover Relvar

Abbreviations

AE, adverse event; CI, confidence interval; FEV1, forced expiratory volume in one second; LS, least square.

Relvar Safety Information4

Contraindications
Hypersensitivity to the active substances or to any of the excipients.

Undesirable effects
Very Common: Headache, Nasopharyngitis.

Common: Infections and infestations, Oropharyngeal pain, Sinusitis, Pharyngitis, Rhinitis, Cough, Dysphonia, Abdominal pain, Arthralgia, Back pain, Fractures, Muscle spasms and Pyrexia.

References
  1. Global Datasheet Fluticasone furoate/vilanterol: v13, September 2022.
  2. Bernstein DI, et al. J Asthma 2015;52:1073–1083.
  3. Braithwaite I, et al. Respir Med 2016;119:115–121.
  4. Relvar Prescribing Information.

GSK does not recommend, endorse, or accept liability for the 3rd party sites.

For more information, please refer to the prescribing information or contact GlaxoSmithKline via gcc.medinfo@gsk.com
To report Adverse Event/s associated with the use of GSK product/s, please contact us via
gulf.safety@gsk.com
To report quality complaint/s associated with the use of GSK product/s, please contact us via
 Gulf.ProductQualityComplaints@gsk.com

Department of Pharmacovigilance & Drug Information
Drug Safety Center
Ministry of Health, Sultanate of Oman
Phone Nos. 0096822357687 / 0096822357690
Fax: 0096822358489
Email: pharma-vigil@moh.gov.om
Website: https://moh.gov.om/en/

دائرة التيقظ و المعلومات الدوائية
مركز سلامة الدواء
وزارة الصحة, سلطنة عمان
هاتف: 0096822357687 / 0096822357690
0096822358489 :فاكس
pharma-vigil@moh.gov.om :البريد االكتروني
https://moh.gov.om/en/ : الموقع االكتروني

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PM-RCH-FFV-WCNT-250001 Date of preparation: July 2025