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Medical History

  • SLE diagnosed 12 years ago
  • Disease has been more active over the past 10 months with new signs and symptoms observed over this time


  • Proteinuria first identified 4 months ago and is ongoing (350 mg/24 h confirmed 1 month ago) – started on mycophenolate mofetil
  • Creatinine clearance of ≥ 30 mL/min and < 60 mL/min
  • Increasing fatigue for 10 months
  • Inflammatory rash for 8 months
  • Persistent myositis for 10 months

Recent Clinical Assessment


  • Hydroxychloroquine 400 mg/day for the last 8 years
  • Prednisone:
    • 5 mg/day for the last 8 years
    • Escalated dose up to 20 mg/day for current renal involvement
  • Mycophenolate mofetil 1000 mg BID for 1 month
  • NSAIDs

Impact on Daily Living

  • The renal involvement has caused anxiety about her condition
  • Her wrist hurts too much to drive a manual car, meaning she has switched to an automatic; she is worried she will have to give up driving
  • She is unable to play golf with her husband and friends due to ongoing muscle weakness and doesn’t feel like attending other social functions due to her rash – her reduction in quality of life has impacted her overall self-esteem and confidence

Learn More About Other SLE Patients

What Next?

Click here to learn more about efficacy of BENLYSTA once-weekly subcutaneous injection

Additional Resources

How do I identify eligible patients in my practice?

*SELENA-SLEDAI (Safety of Estrogens in Lupus Erythematosus: National Assessment version of the Systemic Lupus Erythematosus Disease Activity Index) assesses 24 weighted variables to indicate overall disease severity.
FACIT, functional assessment of chronic illness therapy.

This patient is for illustrative purposes only and is not a real patient.