Efficacy data for SHINGRIX2
Vaccine efficacy profile was studied in subjects ≥50 years old (ZOE-50) and subjects ≥70 years old (ZOE-70). SHINGRIX efficacy profile was also studied in two immunocompromised patient populations aged ≥18 years.2
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The National Advisory Committee on Immunization (NACI) recommends:1
SHINGRIX should be offered to adults ≥50 years of age without contraindications
(strong recommendation).
SHINGRIX should be offered to adults ≥50 years of age without contraindications who have previously been vaccinated with live zoster vaccine
(strong recommendation).
SHINGRIX should be offered to adults ≥50 years of age without contraindications who have had a previous episode of herpes zoster
(strong recommendation).
SHINGRIX may be considered for immunocompromised adults ≥50 years of age
(discretionary recommendation).
According to NACI, a strong recommendation applies to most individuals and should be followed, unless a clear and compelling rationale for an alternative approach is present. A discretionary recommendation may be considered for some individuals in some circumstances. Alternative approaches may be reasonable.1
Refer to the NACI statement on the Public Health Agency website for further information.
© All rights reserved. An Advisory Committee Statement (ACS), National Advisory Committee on Immunization (NACI) – Updated Recommendations on the Use of Herpes Zoster Vaccine. Public Health Agency of Canada modified: 2018. Adapted and reproduced with permission from the Minister of Health, 2018.
References:
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