Efficacy data for SHINGRIX2
Vaccine efficacy profile was studied in subjects ≥50 years old (ZOE-50) and subjects ≥70 years old (ZOE-70). SHINGRIX efficacy profile was also studied in two immunocompromised patient populations aged ≥18 years.2
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The National Advisory Committee on Immunization (NACI) recommends:1
SHINGRIX should be offered to adults ≥50 years of age without contraindications
(strong recommendation).
SHINGRIX should be offered to adults ≥50 years of age without contraindications who have previously been vaccinated with live zoster vaccine
(strong recommendation).
SHINGRIX should be offered to adults ≥50 years of age without contraindications who have had a previous episode of herpes zoster
(strong recommendation).
SHINGRIX may be considered for immunocompromised adults ≥50 years of age
(discretionary recommendation).
According to NACI, a strong recommendation applies to most individuals and should be followed, unless a clear and compelling rationale for an alternative approach is present. A discretionary recommendation may be considered for some individuals in some circumstances. Alternative approaches may be reasonable.1
Refer to the NACI statement on the Public Health Agency website for further information.
References:
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