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QoL preserved
for over 30 cycles of ZEJULA maintenance vs placebo1,2
Figure adapted from González-Martín A, et al. 2019
This analysis is exploratory in nature and does not control for Type 1 error; elements more distal to disease and treatment-related symptoms may be influenced by multiple nondrug factors.2
FOSI QoL domains included: mobility, self-care, anxiety/depression, pain/discomfort and usual activities.
*A treatment cycle lasted 28 days
‡FOSI (Functional Assessment of Cancer Therapy-Ovarian Symptoms Index) is a validated 8-item measure of symptom response to treatment, including lack of energy, vomiting, pain, nausea, stomach swelling, worsening condition, quality of life as assessed by the patient, and cramps in the stomach area.2,5
Figure adapted from Halla K, et al. 2020
Post-surgical patients reported an improvement in fatigue over more than 15 treatment cycles of ZEJULA vs placebo§3
§The analysis was exploratory in nature and did not control for Type 1 error; elements more distal to disease and treatment-related symptoms may have been influenced. In the PRIMA trial, a treatment cycle lasted 28 days.3
EORTC QLQ-C30, European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire; FOSI, Functional Assessment of Cancer Therapy-Ovarian Symptoms Index; MoA, mechanism of action; QoL, quality of life; SE, standard error.
Adverse events should be reported directly to the Health Products Regulatory Authority (HPRA) on their website: www.hpra.ie. Adverse events should also be reported to GlaxoSmithKline on 1800 244 255.
Zejula is a registered trademark of the GlaxoSmithKline group of companies.
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