BEXSERO MOA

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BEXSERO: Mechanism of action 1*

BEXSERO was developed using a multiple antigen approach. Immunization with BEXSERO is intended to raise the titer of bactericidal antibodies that specifically bind the vaccine antigens fHbp, NadA, NHBA, and PorA P1.4 (the immunodominant antigen present in the OMV component). 1*

fHbp
Factor H binding protein

NadA
Neisserial adhesin A

NHBA
Neisseria Heparin Binding Antigen

OMV
Outer Membrane Vesicles that contain PorA 1.4

* Clinical significance unknown.

Reference:

BEXSERO Product Monograph. November 9, 2023.

This page is for Healthcare Professionals only. If you are not a Healthcare Professional, please visit our consumer website BEXSERO.ca .

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