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BEXSERO dosing and administration

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Recommended dosing schedule for BEXSERO 1

The table shows the Recommended dosing schedule for BEXSERO. For a detailed description of the table, please contact GSK customer service at 1-800-387-7374.

BEXSERO should be given by deep intramuscular injection, preferably in the anterolateral aspect of the thigh in infants or in the deltoid muscle region of the upper arm in older subjects. The vaccine must not be mixed with other vaccines or medicinal products in the same syringe.

When given concomitantly with other vaccines, BEXSERO should be administered at a different injection site. BEXSERO must not be mixed with other medicinal products or other vaccines in the same syringe.

Your patients can visit BEXSERO.ca for a handy dose planner. They can also sign up for dose reminders via text or email.

For adolescents and adults aged 11 through 25 years, the interval between doses is not fixed; the second dose can be administered as early as one month after the first dose.
 

BEXSERO provides flexible dosing options intended to fit routine vaccination visits and can be co-administered with other vaccines 1

BEXSERO can be given concomitantly with any of the following vaccine antigens (either as monovalent or as combination vaccines):

  • diphtheria
  • tetanus
  • acellular pertussis
  • H. influenzae type b
  • inactivated poliomyelitis
  • hepatitis B
  • heptavalent pneumococcal conjugate
  • measles
  • mumps
  • rubella
  • varicella
  • meningococcal group C-CRM conjugate

As higher percentages of subjects reported systemic reactions, including fever, change in eating habits, tenderness at the injection site and irritability, following BEXSERO given concomitantly with routine vaccines than after BEXSERO alone, separate vaccinations can be considered when possible. Prophylactic use of acetaminophen reduces the incidence and severity of fever without affecting the immunogenicity of either BEXSERO or most antigens of routine vaccines. The effect of antipyretics other than acetaminophen on the immune response has not been studied.

Concomitant administration of BEXSERO with vaccines other than those mentioned above has not been studied.

BEXSERO should be given by deep intramuscular injection, preferably in the anterolateral aspect of the thigh in infants or in the deltoid muscle region of the upper arm in older subjects.

When given concomitantly with other vaccines, BEXSERO should be administered at a different injection site. BEXSERO must not be mixed with other medicinal products or other vaccines in the same syringe.

Reference:

  1. BEXSERO Product Monograph. February 25, 2019.

This page is for Healthcare Professionals only. If you are not a Healthcare Professional, please visit Bexsero.ca.