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Irish shingles vaccination recommendations for adults ≥ 50 years of age and those aged 18+ at increased risk of herpes zoster.

National Immunisation Advisory Committee (NIAC) Guidelines

When consulting with patients ≥50 years old, consider the NIAC recommendation for shingles vaccination.1 The NIAC Guidelines state that:1,2

  • Shingles vaccination is recommended by NIAC for all adults 65 years and older.2
  • The vaccine may be given to those who have had zoster. It is prudent to defer vaccination for 12 months after the zoster has resolved so that the vaccine can produce a more effective immune response.2
  • As the vaccine is not part of the national immunisation programme, individuals aged ≥50 years wishing to receive it should consult with their GP or pharmacist.2
  • Shingles vaccination is recommended for those 50 years and older with solid organ transplants, cancer, primary or acquired cellular/combined immune deficiencies and immune mediated inflammatory disorders2.
  • Patients with Hodgkin's disease are at particularly high risk, with rates approaching 30% during illness or its treatment.1
<b>>90% Efficacy against Herpes Zoster icon</b>

How efficacious is SHINGRIX?

SHINGRIX demonstrated >90 % efficacy against shingles in adults 50 years of age and older based on pooled data from two large, phase 3 randomised controlled trials.4,5,6

VIEW EFFICACY DATA

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Who can benefit from SHINGRIX?

There is a 1 in 3 lifetime risk of developing shingles.7,8 Age-related decline in immunity puts patients 50 years of age and older at an increased risk of developing shingles.9,10

VIEW PATIENT PROFILES

two syringes showing a two dose schedule

Ready to vaccinate with SHINGRIX?

Familiarise yourself with the dosing and administration of SHINGRIX.4

DOSING AND ADMINISTRATION INFO

References

  1. NIAC. Chapter 3 Immunisation of Immunocompromised Persons. 2022 March. Available on: https://rcpi.access.preservica.com/uncategorized/IO_0ff0fd53-1618-456b-a8b3-52c2bc09e7fd/ Last Accessed: January 2023
  2. NIAC. Chapter 23 Varicella-Zoster. November 2024. Available on https://rcpi.access.preservica.com/uncategorized/IO_b07eb36b-663e-4ba1-a310-8104d8fda480/ Last Accessed: January 2025
  3. National Immunisation guidelines for Ireland, available on https://www.rcpi.ie/Healthcare-Leadership/NIAC/Immunisation-Guidelines-for-Ireland Last Accessed: January 2025
  4. Shingrix, Summary of Product Characteristics (SPC), available on https://www.medicines.ie/medicines/list/all/page-1/per-page-25?query=shingrix. Last Accessed: January 2025
  5. Lal H, Cunningham AL, Godeaux O, Chlibek R, Diez-Domingo J, Hwang S-J, et al. Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. N Engl J Med. 2015 May;372 (22):2087-96.
  6. Cunningham AL, Lal H, Kovac M, Chlibek R, Hwang S-J, Diez-Domingo J, et al. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. N Engl J Med. 2016 Sep;375 (11):1019-32.
  7. Harpaz R, et al. MMWR Recomm Rep. 2008 June;57(RR-5):1-30. 2. Zerboni L, et al. Nat Rev Microbiol. 2014 Mar;12 (3):197-210.
  8. Bollaerts K et al. A systematic review of varicella seroprevaience in European countries before universal childhood immunization: deriving incidence from seroprevaience data. Epidemiol. Infect. (2017), 145, 2666-2677
  9. Kimberlin DW, Whitley RJ. Varicella-zoster vaccine for the prevention of herpes zoster. N Engl J Med. 2007 Mar;356 (13):1338-43.
  10. Crooke, S.N., et al. Immun Ageing. 2019 Sep 13; 16:25.

Adverse events should be reported directly to the Health Products Regulatory Authority (HPRA) on their website: www.hpra.ie. Adverse events should also be reported to GlaxoSmithKline on 1800 244 255.

SHINGRIX is owned by or licensed to the GSK group of companies.
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Trade marks are owned by or licensed to the GSK group of companies.

PM-IE-SGX-WCNT-220006
Date of Preparation: January 2025