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ZEJULA is indicated:1
- as monotherapy for the maintenance treatment of adult patients with advanced epithelial (FIGO Stages III and IV) high-grade ovarian, fallopian tube or primary peritoneal cancer who are in response (complete or partial) following completion of first-line platinum-based chemotherapy.
- as monotherapy for the maintenance treatment of adult patients with platinum- based relapsed high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in response (complete or partial) to platinum-based chemotherapy.
References
- ZEJULA (niraparib) Summary of Product Characteristics. September 2025.
Abbreviations
1L, first-line; aOC, advanced ovarian cancer; CA-125, cancer antigen 125; ESMO, European Society for Medical Oncology; FIGO, Federation of Gynaecology and Obstetrics; MDT, multidisciplinary team; MoA, mechanism of action; PARPi, poly(ADP-ribose) polymerase inhibitor; RECIST, Response Evaluation Criteria in Solid Tumors.
Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk or search for MHRA Yellowcard in the Google Play or Apple App store. Adverse events should also be reported to GlaxoSmithKline on 0800 221 4411 or UKSafety@gsk.com
February 2026 | PM-GB-NRP-WCNT-240024
