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Current available safety data on Maternal Immunization with Tdap does not indicate an increase in adverse effects on pregnancy outcomes or on the health of the fetus/newborn child. 12
BOOSTRIX is indicated for booster vaccination against diphtheria, tetanus and pertussis of individuals aged 4 years and older
Maternal Immunization with a Tdap vaccine has shown to be effective in preventing pertussis disease in infants <3 months of age 3-5
In this section:
Is Maternal Immunization safe?
Is Maternal Immunization effective?
Tdap: tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine
References :
- Munoz FM. Pertussis vaccine in pregnant women: safety and uptake. Vaccine Develop Ther. 2016;6:1-8. [accessed March 2018]; Available at: https://www.dovepress.com/pertussis-vaccine-in-pregnant-women-safety-and-uptake-peer-reviewed-fulltext-article-VDT#
- GlaxoSmithKline Biologicals. BOOSTRIX Summary of Product Characteristics. 2017.
- Amirthalingam G, et al. Sustained effectiveness of the maternal pertussis immunization program in England 3 years following introduction. Clin Infect Dis. 2016;63(suppl 4):S236-S243.
- Bellido-Blasco J, et al. A case-control study to assess the effectiveness of pertussis vaccination during pregnancy on newborns, Valencian community, Spain, 1 March 2015 to 29 February 2016. Euro Surveillance. 017;22(22):1-7.
- Saul N, et al. Effectiveness of maternal pertussis vaccination in preventing infection and disease in infants: The NSW Public Health Network case-control study. Vaccine. 2018;36(14):1887-1892.
