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According to CDC, 76% of pertussis-related deaths occur in infants aged under 2 months 1

  • Infants do not begin their own primary vaccine series against pertussis (with diphtheria, tetanus toxoid and pertussis) until approximately 2 months of age, 5 leaving them unprotected during the highly vulnerable newborn period 2 3
  • Pertussis disease can occur in all age groups, but can cause serious and life-threatening complications in unvaccinated, vulnerable newborns and young infants 4 5
  • Infants under 2 months of age account for most severe pertussis cases, hospitalizations, and deaths due to pertussis 5 6

Newborns and young infants are at highest risk of fatal outcomes from pertussis 7 8

 

CDC: Centers for Disease Control and Prevention.

References:

  1. The National Vaccine Advisory Committee: reducing patient and provider barriers to maternal immunizations: approved by the National Advisory Committee on June 11, 2014. Public Health Rep. 2015;130:10-42. [accessed February 2018]; Available at: https://ncbi.nlm.nih.gov/pmc/articles/PMC4245282/
  2. CDC Recommended immunization for children. Updated Dec 2016. [accessed March 2018]; Available at: https://www.cdc.gov/vaccines/schedule/easy-to-read/child.html#print
  3. ACOG Committee Opinion. Update on immunization and pregnancy: tetanus, diphtheria, and pertussis vaccination. Number 718, September 2017. [accessed March 2018]; Available at: https://www.acog.org/Resources-And-Publications/Committee-Opinions/Committee-on-Obstetric-Practice/Update-on-Immunization-and-Pregnancy-Tetanus-Diphtheria-and-Pertussis-Vaccination
  4. Centers for Disease Control (CDC). Pertussis (Whooping Cough). [accessed March 2018]; Available at: https://www.cdc.gov/pertussis/index.html
  5. Tiwari TS, et al. First pertussis vaccine dose and prevention of infant mortality. Pediatrics. 2015;135:990-999.
  6. Gkentzi D, et al. Maternal vaccination against pertussis: a systematic review of the recent literature. Arch Dis Child Fetal Neonatal Ed. 2017;102:F456-F463.
  7. Hong JY. Update on pertussis and pertussis immunization. Korean J Pediatr. 2010;53:629-633.
  8. Healy CM. Pertussis vaccination in pregnancy. Hum Vaccin Immunother. 2016;12(8):1972-1981.